HitPredict

Interactor 1: HCN1 (O60741)
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1)
Gene: HCN1

Interactor 2: ILEU (P30740)
Leukocyte elastase inhibitor (LEI) (Monocyte/neutrophil elastase inhibitor) (EI) (M/NEI) (Peptidase inhibitor 2) (PI-2) (Serpin B1)
Gene: SERPINB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 890 Hs			1 379
+	Hs
		239852 HCN1_HUMAN (1-890): 0: 684: 100.00		SPB4_HUMAN (1-379): 3.54e-155: 443: 48.23
+	Hs
		239801 HCN1_HUMAN (1-890): 0: 684: 100.00		SPB3_HUMAN (1-379): 2.22e-153: 439: 48.23
+	Hs
		239683 HCN1_HUMAN (1-890): 0: 684: 100.00		AACT_HUMAN (4-379): 4.5e-146: 421: 34.47
+	Hs
		239827 HCN1_HUMAN (1-890): 0: 684: 100.00		SPB5_HUMAN (1-379): 1.41e-144: 416: 39.31
+	Hs
		239682 HCN1_HUMAN (1-890): 0: 684: 100.00		A1AT_HUMAN (2-379): 5.31e-143: 413: 30.63