HitPredict

Interactor 1: HCN1 (O60741)
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1)
Gene: HCN1

Interactor 2: JKIP1 (Q96N16)
Janus kinase and microtubule-interacting protein 1 (GABA-B receptor-binding protein) (Multiple alpha-helices and RNA-linker protein 1) (Marlin-1)
Gene: JAKMIP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	37207277
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 890 Hs			1 626
+	Hs
		240041 HCN1_HUMAN (1-890): 0: 684: 100.00		JKIP3_HUMAN (6-606): 1.72e-47: 180: 58.93
+	Hs
		240127 HCN1_HUMAN (1-890): 0: 684: 100.00		JKIP2_HUMAN (1-607): 2.41e-35: 144: 60.86
+	Hs
		240199 HCN1_HUMAN (1-890): 0: 684: 100.00		MYO5C_HUMAN (109-597): 2.06e-23: 107: 13.29
+	Hs
		239820 HCN1_HUMAN (1-890): 0: 684: 100.00		MYH10_HUMAN (131-626): 3.03e-22: 104: 13.05
+	Hs
		240310 HCN1_HUMAN (1-890): 0: 684: 100.00		MRCKB_HUMAN (14-489): 2.22e-16: 85.5: 13.47
+	Hs
		239819 HCN1_HUMAN (1-890): 0: 684: 100.00		MYH9_HUMAN (2-446): 1.49e-15: 82.7: 11.40
+	Mm
		292118 HCN1_MOUSE (1-890): 0: 651: 90.35		CTRO_MOUSE (4-588): 4.23e-23: 107: 14.31
+	Hs
		240047 HCN1_HUMAN (1-890): 0: 684: 100.00		MRCKG_HUMAN (59-450): 4.63e-12: 71.7: 13.93
+	Hs
		239640 HCN1_HUMAN (1-890): 0: 684: 100.00		KI21B_HUMAN (7-611): 2.49e-11: 69.4: 14.40
+	Hs
		240068 HCN1_HUMAN (1-890): 0: 684: 100.00		MYH14_HUMAN (1-604): 1.39e-10: 66.7: 11.50
+	Hs
		240116 HCN1_HUMAN (1-890): 0: 684: 100.00		MY18A_HUMAN (236-622): 8.42e-10: 64.2: 10.85