HitPredict

Interactor 1: HCN1 (O60741)
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1)
Gene: HCN1

Interactor 2: PCDA2 (Q9Y5H9)
Protocadherin alpha-2 (PCDH-alpha-2)
Gene: PCDHA2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	37207277
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 890 Hs			1 948
+	Hs
		240268 HCN1_HUMAN (1-890): 0: 684: 100.00		PCDA4_HUMAN (1-948): 0: 1116: 83.02
+	Hs
		240308 HCN1_HUMAN (1-890): 0: 684: 100.00		PCDA1_HUMAN (1-948): 0: 1107: 83.26
+	Hs
		240305 HCN1_HUMAN (1-890): 0: 684: 100.00		PCDA8_HUMAN (1-948): 0: 1104: 79.37
+	Hs
		240307 HCN1_HUMAN (1-890): 0: 684: 100.00		PCDAB_HUMAN (1-948): 0: 1101: 81.16
+	Hs
		240269 HCN1_HUMAN (1-890): 0: 684: 100.00		PCDAC_HUMAN (1-948): 0: 1079: 80.49
+	Hs
		240303 HCN1_HUMAN (1-890): 0: 684: 100.00		PCDG6_HUMAN (1-896): 0: 979: 38.76
+	Hs
		240302 HCN1_HUMAN (1-890): 0: 684: 100.00		PCDGD_HUMAN (1-896): 0: 969: 37.66
+	Hs
		240304 HCN1_HUMAN (1-890): 0: 684: 100.00		PCDG3_HUMAN (25-896): 0: 964: 37.89
+	Hs
		240300 HCN1_HUMAN (1-890): 0: 684: 100.00		PCDGL_HUMAN (7-896): 0: 955: 36.85
+	Hs
		240301 HCN1_HUMAN (1-890): 0: 684: 100.00		PCDGI_HUMAN (2-896): 0: 944: 35.52
+	Hs
		240295 HCN1_HUMAN (1-890): 0: 684: 100.00		PCDB5_HUMAN (1-801): 0: 923: 38.00
+	Hs
		240203 HCN1_HUMAN (1-890): 0: 684: 100.00		PCDBG_HUMAN (1-781): 0: 920: 38.58
+	Hs
		240296 HCN1_HUMAN (1-890): 0: 684: 100.00		PCDB3_HUMAN (1-798): 0: 907: 38.14
+	Hs
		240298 HCN1_HUMAN (1-890): 0: 684: 100.00		PCDBF_HUMAN (1-789): 0: 905: 41.58
+	Hs
		240309 HCN1_HUMAN (1-890): 0: 684: 100.00		PCDC2_HUMAN (4-447): 1.79e-96: 328: 25.55
+	Hs
		240267 HCN1_HUMAN (1-890): 0: 684: 100.00		PCDGG_HUMAN (3-447): 1.25e-93: 318: 26.54