HitPredict

Interactor 1: SNX2 (O60749)
Sorting nexin-2 (Transformation-related gene 9 protein) (TRG-9)
Gene: SNX2

Interactor 2: DYN2 (P50570)
Dynamin-2 (EC 3.6.5.5) (Dynamin 2) (Dynamin II)
Gene: DNM2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~PX
Common GO terms	GO:0005737 - cytoplasm GO:0005768 - endosome GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 519 Hs			1 870
+	Hs
		240458 SNX2_HUMAN (1-519): 5.7e-150: 440: 100.00		DYN3_HUMAN (1-870): 0: 994: 78.41
+	Hs
		1040534 SNX1_HUMAN (2-519): 1.54e-123: 373: 59.32		DYN3_HUMAN (1-870): 0: 994: 78.41
+	Hs
		840879 SNX9_HUMAN (3-515): 6.14e-93: 296: 16.64		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		840797 SNX18_HUMAN (4-474): 2.52e-78: 259: 15.31		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		840772 SNX33_HUMAN (47-518): 7.22e-78: 256: 14.52		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		983421 SNX9_HUMAN (3-515): 6.14e-93: 296: 16.64		DYN1_HUMAN (1-846): 0: 1002: 79.04
+	Hs
		1357820 SNX9_HUMAN (3-515): 6.14e-93: 296: 16.64		DYN3_HUMAN (1-870): 0: 994: 78.41
+	Hs
		2824 SNX9_HUMAN (3-515): 6.14e-93: 296: 16.64		A0A0D9SFE4_HUMAN (1-851): 0: 994: 78.11
+	Hs
		983396 SNX33_HUMAN (47-518): 7.22e-78: 256: 14.52		DYN1_HUMAN (1-846): 0: 1002: 79.04
+	Hs
		1261052 SNX33_HUMAN (47-518): 7.22e-78: 256: 14.52		DYN3_HUMAN (1-870): 0: 994: 78.41
+	Hs
		1357821 SNX5_HUMAN (123-517): 2.28e-68: 227: 22.89		DYN3_HUMAN (1-870): 0: 994: 78.41
+	Hs
		1357510 SNX6_HUMAN (113-517): 4.05e-68: 226: 19.06		DYN3_HUMAN (1-870): 0: 994: 78.41
+	Ce
		760504 LST4_CAEEL (2-516): 6.83e-68: 230: 15.27		DYN1_CAEEL (3-823): 0: 899: 61.86