Interactor 1: SNX2 (O60749)
Sorting nexin-2 (Transformation-related gene 9 protein) (TRG-9)
Gene: SNX2

Interactor 2: SNX6 (Q9UNH7)
Sorting nexin-6 (TRAF4-associated factor 2) [Cleaved into: Sorting nexin-6, N-terminally processed]
Gene: SNX6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.963

The method score is based on:

Property Details
Experiments 32296183, 33961781, 11279102, 35271311, 37071682, 21988832, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, cross-linking study, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PX~PX, PX~Vps5, Vps5~Vps5
Common GO terms GO:0005737 - cytoplasm
GO:0005764 - lysosome
GO:0005768 - endosome
GO:0005829 - cytosol
GO:0006886 - intracellular protein transport
and 6 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 519
Hs

1 406
+ Hs
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+ Ce
+ Hs
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+ At
+ Ce
+ At
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+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024