HitPredict

Interactor 1: H2B1K (O60814)
Histone H2B type 1-K (H2B K) (HIRA-interacting protein 1)
Gene: H2BC12

Interactor 2: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	31239290, 32416067, 34349018
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 1362
+	Hs
		243805 H2B1J_HUMAN (1-126): 6.13e-54: 166: 99.21		BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00
+	Hs
		244236 H2B1C_HUMAN (1-126): 1.07e-53: 166: 99.21		BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00
+	Hs
		244513 H2B2E_HUMAN (1-126): 5.55e-54: 166: 98.41		BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00
+	Hs
		244752 H2B1H_HUMAN (1-126): 5.43e-54: 166: 98.41		BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00
+	Hs
		1066994 H2B2F_HUMAN (1-126): 2.19e-54: 168: 97.62		BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53
+	Hs
		631389 H2B1C_HUMAN (1-126): 1.07e-53: 166: 99.21		BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43
+	Hs
		631445 H2B2E_HUMAN (1-126): 5.55e-54: 166: 98.41		BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43
+	Hs
		918378 H2B1C_HUMAN (1-126): 1.07e-53: 166: 99.21		BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53
+	Hs
		319121 H2B1O_HUMAN (1-126): 2.88e-54: 167: 97.62		BRD1_HUMAN (197-781): 8.89e-33: 140: 13.99
+	Hs
		319162 H2B1C_HUMAN (1-126): 1.07e-53: 166: 99.21		BRD1_HUMAN (197-781): 8.89e-33: 140: 13.99
+	Hs
		319214 H2B2E_HUMAN (1-126): 5.55e-54: 166: 98.41		BRD1_HUMAN (197-781): 8.89e-33: 140: 13.99
+	Hs
		1087312 H2B2E_HUMAN (1-126): 5.55e-54: 166: 98.41		KAT2B_HUMAN (327-456): 5.61e-22: 105: 26.92
+	Hs
		1087311 H2B2E_HUMAN (1-126): 5.55e-54: 166: 98.41		KAT2A_HUMAN (327-456): 1.76e-20: 100: 26.15
+	Hs
		1087228 H2B2E_HUMAN (1-126): 5.55e-54: 166: 98.41		PB1_HUMAN (26-956): 2.35e-19: 97.1: 10.81
+	Hs
		918481 H2B1C_HUMAN (1-126): 1.07e-53: 166: 99.21		PB1_HUMAN (26-956): 2.35e-19: 97.1: 10.81
+	Hs
		1087293 H2B2E_HUMAN (1-126): 5.55e-54: 166: 98.41		PHIP_HUMAN (26-669): 5.56e-18: 92.9: 13.30
+	Hs
		918554 H2B1C_HUMAN (1-126): 1.07e-53: 166: 99.21		PHIP_HUMAN (26-669): 5.56e-18: 92.9: 13.30
+	Hs
		1017308 H2B2E_HUMAN (1-126): 5.55e-54: 166: 98.41		BPTF_HUMAN (67-161): 9.86e-11: 68.9: 41.05
+	Hs
		1017333 H2B1H_HUMAN (1-126): 5.43e-54: 166: 98.41		BPTF_HUMAN (67-161): 9.86e-11: 68.9: 41.05
+	Hs
		918323 H2B1C_HUMAN (1-126): 1.07e-53: 166: 99.21		BPTF_HUMAN (67-161): 9.86e-11: 68.9: 41.05