HitPredict

Interactor 1: H2B1K (O60814)
Histone H2B type 1-K (H2B K) (HIRA-interacting protein 1)
Gene: H2BC12

Interactor 2: RPB1 (P24928)
DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (3'-5' exoribonuclease) (EC 3.1.13.-) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) (RNA-directed RNA polymerase II subunit RPB1) (EC 2.7.7.48)
Gene: POLR2A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34349018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 126 Hs			1 1970
+	Hs
		420805 H2B1J_HUMAN (1-126): 6.13e-54: 166: 99.21		RPB1_HUMAN (1-1611): 0: 1858: 100.00
+	Hs
		624851 H2B1C_HUMAN (1-126): 1.07e-53: 166: 99.21		RPB1_HUMAN (1-1611): 0: 1858: 100.00
+	Hs
		624917 H2B2E_HUMAN (1-126): 5.55e-54: 166: 98.41		RPB1_HUMAN (1-1611): 0: 1858: 100.00
+	Hs
		624984 H2B1H_HUMAN (1-126): 5.43e-54: 166: 98.41		RPB1_HUMAN (1-1611): 0: 1858: 100.00
+	Hs
		624835 H2B1D_HUMAN (1-126): 3.17e-53: 164: 98.41		RPB1_HUMAN (1-1611): 0: 1858: 100.00
+	Hs
		625015 H2B1L_HUMAN (1-126): 2.18e-52: 163: 97.62		RPB1_HUMAN (1-1611): 0: 1858: 100.00
+	Sc
		355717 H2B2_YEAST (3-125): 7.25e-37: 123: 70.73		RPB1_YEAST (11-1592): 0: 1458: 48.49
+	Sc
		355285 H2B1_YEAST (3-125): 3e-36: 122: 70.73		RPB1_YEAST (11-1592): 0: 1458: 48.49
+	Sc
		355718 H2B2_YEAST (3-125): 7.25e-37: 123: 70.73		RPC1_YEAST (11-1471): 0: 1356: 32.85
+	Sc
		355286 H2B1_YEAST (3-125): 3e-36: 122: 70.73		RPC1_YEAST (11-1471): 0: 1356: 32.85
+	Hs
		317082 H2B1B_HUMAN (1-126): 1.52e-53: 165: 96.83		RPA1_HUMAN (960-1473): 4.35e-38: 159: 16.12