HitPredict

Interactor 1: CCD22 (O60826)
Coiled-coil domain-containing protein 22
Gene: CCDC22

Interactor 2: COMDA (Q9Y6G5)
COMM domain-containing protein 10
Gene: COMMD10

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	0.60	0.728

Property	Details
Experiments	26496610, 33961781, 35271311, 28514442, 23563313
Identification Methods	affinity chromatography technology, tandem affinity purification, anti bait coimmunoprecipitation, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 627 Hs			1 202
+	Hs
		241826 CCD22_HUMAN (1-627): 9.22e-129: 394: 100.00		COMD3_HUMAN (9-202): 2.18e-61: 191: 21.32
+	Hs
		241777 CCD22_HUMAN (1-627): 9.22e-129: 394: 100.00		COMD7_HUMAN (10-200): 3.3e-59: 186: 14.14
+	Hs
		241810 CCD22_HUMAN (1-627): 9.22e-129: 394: 100.00		COMD5_HUMAN (12-201): 1.57e-46: 154: 17.01
+	Hs
		241812 CCD22_HUMAN (1-627): 9.22e-129: 394: 100.00		COMD4_HUMAN (9-201): 6.36e-43: 144: 20.73
+	Hs
		241778 CCD22_HUMAN (1-627): 9.22e-129: 394: 100.00		COMD2_HUMAN (7-198): 2.37e-09: 56.4: 11.98
+	Hs
		1132681 FKB15_HUMAN (90-625): 4.93e-44: 171: 17.14		COMDA_HUMAN (1-202): 2.25e-60: 188: 100.00
+	Hs
		1299187 MIA2_HUMAN (290-625): 1.91e-21: 101: 12.36		COMD3_HUMAN (9-202): 2.18e-61: 191: 21.32
+	Dm
		1374722 CCD22_DROME (325-625): 1.9e-16: 84.6: 29.14		Q9VYV9_DROME (42-201): 4.51e-37: 130: 27.78
+	Hs
		1204175 MIA2_HUMAN (290-625): 1.91e-21: 101: 12.36		COMD2_HUMAN (7-198): 2.37e-09: 56.4: 11.98