HitPredict

Interactor 1: DKC1 (O60832)
H/ACA ribonucleoprotein complex subunit DKC1 (EC 5.4.99.-) (CBF5 homolog) (Dyskerin) (Nopp140-associated protein of 57 kDa) (Nucleolar protein NAP57) (Nucleolar protein family A member 4) (snoRNP protein DKC1)
Gene: DKC1

Interactor 2: ZCRB1 (Q8TBF4)
Zinc finger CCHC-type and RNA-binding motif-containing protein 1 (U11/U12 small nuclear ribonucleoprotein 31 kDa protein) (U11/U12 snRNP 31 kDa protein) (U11/U12-31K)
Gene: ZCRB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 514 Hs			1 217
+	Hs
		242532 DKC1_HUMAN (1-514): 0: 779: 100.00		PABP5_HUMAN (1-179): 2.36e-39: 140: 15.54
+	Hs
		242476 DKC1_HUMAN (1-514): 0: 779: 100.00		SRSF7_HUMAN (9-120): 7.54e-35: 125: 32.17
+	Hs
		242559 DKC1_HUMAN (1-514): 0: 779: 100.00		RBM4_HUMAN (11-103): 1.52e-18: 84.2: 21.51
+	Sc
		376706 CBF5_YEAST (33-472): 0: 633: 63.17		PABP_YEAST (11-208): 3.81e-23: 98.5: 15.60