Interactor 1: DKC1 (O60832)
H/ACA ribonucleoprotein complex subunit DKC1 (EC 5.4.99.-) (CBF5 homolog) (Dyskerin) (Nopp140-associated protein of 57 kDa) (Nucleolar protein NAP57) (Nucleolar protein family A member 4) (snoRNP protein DKC1)
Gene: DKC1

Interactor 2: TCAB1 (Q9BUR4)
Telomerase Cajal body protein 1 (WD repeat-containing protein 79) (WD40 repeat-containing protein antisense to TP53 gene) (WRAP53beta)
Gene: WRAP53

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 0.60 0.721

The method score is based on:

Property Details
Experiments 26496610, 25416818, 33961781, 25467444, 19179534
Identification Methods affinity chromatography technology, protein complementation assay, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0005697 - telomerase holoenzyme complex
GO:0007004 - telomere maintenance via telomerase
GO:0051973 - positive regulation of telomerase activity
and 3 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 514
Hs

1 548
+ Hs
+ Hs
+ Hs
+ Sc

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Last updated: 15 Jul 2024