HitPredict

Interactor 1: TRI13 (O60858)
E3 ubiquitin-protein ligase TRIM13 (EC 2.3.2.27) (B-cell chronic lymphocytic leukemia tumor suppressor Leu5) (Leukemia-associated protein 5) (Putative tumor suppressor RFP2) (RING finger protein 77) (RING-type E3 ubiquitin transferase TRIM13) (Ret finger protein 2) (Tripartite motif-containing protein 13)
Gene: TRIM13

Interactor 2: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)
Gene: SQSTM1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31375263, 22178386
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0008270 - zinc ion binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 407 Hs			1 440
+	Hs
		584950 RO52_HUMAN (1-321): 7.08e-74: 240: 15.74		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Hs
		1036807 TRI11_HUMAN (3-319): 8.55e-70: 229: 18.24		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Hs
		536812 TRI27_HUMAN (2-324): 1.55e-65: 219: 16.81		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Hs
		1036876 TRIM5_HUMAN (1-304): 2.82e-65: 218: 17.53		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Hs
		1019298 TRI26_HUMAN (1-335): 1.52e-60: 206: 14.85		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Hs
		1036706 TRI50_HUMAN (1-325): 9.17e-57: 195: 20.42		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Hs
		1036872 TRI55_HUMAN (1-293): 5.32e-54: 189: 22.80		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Hs
		1036785 TRI63_HUMAN (1-285): 9.86e-55: 186: 22.67		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Mm
		102616 TRI55_MOUSE (1-293): 6.67e-57: 197: 22.48		SQSTM_MOUSE (1-440): 0: 731: 90.72
+	Mm
		548985 TR30A_MOUSE (1-301): 3.09e-57: 196: 17.71		SQSTM_MOUSE (1-440): 0: 731: 90.72
+	Hs
		584963 RO52_HUMAN (1-321): 7.08e-74: 240: 15.74		NBR1_HUMAN (80-184): 5.95e-10: 63.6: 24.78