HitPredict

Interactor 1: DIAP2 (O60879)
Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2)
Gene: DIAPH2

Interactor 2: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Drf_FH3~Ras, Drf_GBD~Ras
Common GO terms	GO:0005769 - early endosome GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1101 Hs			1 196
+	Hs
		925658 DIAP3_HUMAN (13-1093): 0: 886: 56.56		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		900958 DIAP3_HUMAN (13-1093): 0: 886: 56.56		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		916010 DIAP3_HUMAN (13-1093): 0: 886: 56.56		RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00
+	Hs
		545645 DIAP3_HUMAN (13-1093): 0: 886: 56.56		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Hs
		436532 DIAP3_HUMAN (13-1093): 0: 886: 56.56		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		951386 DIAP3_HUMAN (13-1093): 0: 886: 56.56		RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53
+	Hs
		892621 DIAP3_HUMAN (13-1093): 0: 886: 56.56		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54
+	Hs
		894489 DIAP3_HUMAN (13-1093): 0: 886: 56.56		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		564704 DIAP3_HUMAN (13-1093): 0: 886: 56.56		RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74
+	Hs
		120664 DIAP3_HUMAN (13-1093): 0: 886: 56.56		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98
+	Hs
		925531 FMNL2_HUMAN (91-1091): 0: 651: 22.60		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		900815 FMNL2_HUMAN (91-1091): 0: 651: 22.60		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		915901 FMNL2_HUMAN (91-1091): 0: 651: 22.60		RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00
+	Hs
		436466 FMNL2_HUMAN (91-1091): 0: 651: 22.60		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		894328 FMNL2_HUMAN (91-1091): 0: 651: 22.60		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		900661 FMNL3_HUMAN (91-1091): 0: 642: 21.57		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		545484 FMNL3_HUMAN (91-1091): 0: 642: 21.57		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Hs
		894190 FMNL3_HUMAN (91-1091): 0: 642: 21.57		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		120589 FMNL2_HUMAN (91-1091): 0: 651: 22.60		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98
+	Dd
		710114 FORH_DICDI (72-1074): 0: 606: 20.76		RAC1A_DICDI (1-196): 1.18e-80: 239: 52.04