HitPredict

Interactor 1: SH21A (O60880)
SH2 domain-containing protein 1A (Duncan disease SH2-protein) (Signaling lymphocytic activation molecule-associated protein) (SLAM-associated protein) (T-cell signal transduction molecule SAP)
Gene: SH2D1A

Interactor 2: FOS (P01100)
Protein c-Fos (Cellular oncogene fos) (Fos proto-oncogene, AP-1 transcription factor subunit) (G0/G1 switch regulatory protein 7) (Proto-oncogene c-Fos) (Transcription factor AP-1 subunit c-Fos)
Gene: FOS

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 128 Hs			1 380
+	Hs
		337295 ABL1_HUMAN (1-127): 4.39e-40: 143: 26.72		FOS_HUMAN (1-380): 1.68e-84: 263: 100.00
+	Hs
		155823 SH21B_HUMAN (5-119): 1.69e-34: 117: 42.61		FOS_HUMAN (1-380): 1.68e-84: 263: 100.00
+	Hs
		337332 ABL1_HUMAN (1-127): 4.39e-40: 143: 26.72		FOSL1_HUMAN (59-287): 1.43e-34: 130: 37.61
+	Hs
		337306 ABL1_HUMAN (1-127): 4.39e-40: 143: 26.72		JUN_HUMAN (48-215): 1.19e-23: 102: 16.47
+	Hs
		243128 SH21A_HUMAN (1-128): 3.11e-38: 127: 100.00		ATF3_HUMAN (131-215): 4.23e-25: 102: 43.53
+	Hs
		401572 CSK_HUMAN (1-126): 1.42e-34: 125: 25.40		JUN_HUMAN (48-215): 1.19e-23: 102: 16.47