HitPredict

Interactor 1: SH21A (O60880)
SH2 domain-containing protein 1A (Duncan disease SH2-protein) (Signaling lymphocytic activation molecule-associated protein) (SLAM-associated protein) (T-cell signal transduction molecule SAP)
Gene: SH2D1A

Interactor 2: KCC2G (Q13555)
Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II subunit gamma) (CaMK-II subunit gamma) (EC 2.7.11.17)
Gene: CAMK2G

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 128 Hs			1 558
+	Hs
		433348 YES_HUMAN (1-127): 2.68e-40: 142: 19.40		KCC2G_HUMAN (1-558): 0: 672: 100.00
+	Hs
		433508 YES_HUMAN (1-127): 2.68e-40: 142: 19.40		KCC2A_HUMAN (1-555): 0: 550: 65.23
+	Hs
		176444 SHIP2_HUMAN (3-122): 1.12e-34: 128: 37.50		KCC2D_HUMAN (1-558): 0: 525: 64.88
+	Hs
		243140 SH21A_HUMAN (1-128): 3.11e-38: 127: 100.00		KCC2D_HUMAN (1-558): 0: 525: 64.88
+	Hs
		924549 GRB2_HUMAN (1-123): 1.97e-35: 122: 19.69		KCC2D_HUMAN (1-558): 0: 525: 64.88
+	Hs
		411778 LCK_HUMAN (1-125): 4.76e-41: 143: 19.08		MARK2_HUMAN (2-556): 4.99e-141: 428: 24.16
+	Hs
		433850 LYN_HUMAN (1-125): 1.04e-39: 140: 19.85		MARK2_HUMAN (2-556): 4.99e-141: 428: 24.16
+	Hs
		846470 BLK_HUMAN (1-125): 7.14e-38: 135: 18.46		KCC1A_HUMAN (6-336): 4.19e-138: 406: 37.76
+	Hs
		159139 HCK_HUMAN (1-127): 3.37e-42: 147: 20.30		CSKP_HUMAN (10-308): 2.84e-83: 280: 46.08
+	Hs
		159138 LYN_HUMAN (1-125): 1.04e-39: 140: 19.85		CSKP_HUMAN (10-308): 2.84e-83: 280: 46.08
+	Hs
		789119 FRK_HUMAN (1-123): 1.33e-36: 131: 23.39		KCC4_HUMAN (10-304): 2.82e-72: 240: 43.43
+	Hs
		454830 FGR_HUMAN (1-126): 6.18e-38: 135: 20.30		KCC2B_HUMAN (287-558): 1.59e-57: 205: 49.29
+	Hs
		243138 SH21A_HUMAN (1-128): 3.11e-38: 127: 100.00		KCC2B_HUMAN (287-558): 1.59e-57: 205: 49.29
+	Ce
		220204 SRC2_CAEEL (1-125): 3.62e-38: 136: 25.58		KCC2D_CAEEL (269-555): 4.5e-31: 130: 28.71