HitPredict

Interactor 1: SH21A (O60880)
SH2 domain-containing protein 1A (Duncan disease SH2-protein) (Signaling lymphocytic activation molecule-associated protein) (SLAM-associated protein) (T-cell signal transduction molecule SAP)
Gene: SH2D1A

Interactor 2: SIGL7 (Q9Y286)
Sialic acid-binding Ig-like lectin 7 (Siglec-7) (Adhesion inhibitory receptor molecule 1) (AIRM-1) (CDw328) (D-siglec) (QA79 membrane protein) (p75) (CD antigen CD328)
Gene: SIGLEC7

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	19150402
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 128 Hs			1 467
+	Hs
		211413 SH21A_HUMAN (1-128): 3.11e-38: 127: 100.00		SIGL6_HUMAN (16-467): 1.26e-89: 282: 48.79
+	Mm
		56907 FYN_MOUSE (1-125): 4.62e-37: 133: 18.52		PTPRF_MOUSE (2-460): 2.9e-56: 203: 13.32
+	Dm
		219802 ABL_DROME (1-127): 2.37e-39: 141: 27.82		O44924_DROME (16-453): 1.92e-47: 177: 12.12
+	Hs
		433742 LYN_HUMAN (1-125): 1.04e-39: 140: 19.85		PTK7_HUMAN (22-446): 2.06e-31: 130: 11.94
+	Hs
		177593 SH21A_HUMAN (1-128): 3.11e-38: 127: 100.00		SIGL5_HUMAN (39-467): 8.62e-35: 138: 18.74
+	Hs
		434111 LYN_HUMAN (1-125): 1.04e-39: 140: 19.85		ROBO1_HUMAN (15-275): 4.15e-24: 108: 12.31
+	Hs
		522764 SRC_HUMAN (1-127): 8.71e-39: 138: 20.90		CD33_HUMAN (145-465): 8.84e-26: 109: 18.38
+	Hs
		433569 LYN_HUMAN (1-125): 1.04e-39: 140: 19.85		CD22_HUMAN (31-354): 2.73e-23: 105: 16.31
+	Hs
		412004 FYN_HUMAN (1-125): 4.91e-37: 133: 18.52		MAG_HUMAN (24-466): 1.12e-24: 109: 12.93
+	Hs
		590610 SHIP1_HUMAN (4-103): 1.66e-37: 136: 43.00		CD22_HUMAN (31-354): 2.73e-23: 105: 16.31
+	Hs
		433249 YES_HUMAN (1-127): 2.68e-40: 142: 19.40		VCAM1_HUMAN (107-363): 1.98e-19: 93.3: 18.02
+	Mm
		722908 SHIP1_MOUSE (4-103): 9.63e-37: 133: 42.00		CD22_MOUSE (20-365): 6.37e-22: 101: 17.61
+	Hs
		243129 SH21A_HUMAN (1-128): 3.11e-38: 127: 100.00		CD22_HUMAN (31-354): 2.73e-23: 105: 16.31
+	Hs
		590607 GRB2_HUMAN (1-123): 1.97e-35: 122: 19.69		CD22_HUMAN (31-354): 2.73e-23: 105: 16.31
+	Hs
		523003 SRC_HUMAN (1-127): 8.71e-39: 138: 20.90		MYLK_HUMAN (248-338): 2.37e-17: 87.5: 20.20
+	Mm
		722901 GRB2_MOUSE (1-123): 1.02e-35: 123: 19.69		CD22_MOUSE (20-365): 6.37e-22: 101: 17.61
+	Hs
		176379 SHIP2_HUMAN (3-122): 1.12e-34: 128: 37.50		VCAM1_HUMAN (107-363): 1.98e-19: 93.3: 18.02
+	Hs
		581649 GRB2_HUMAN (1-123): 1.97e-35: 122: 19.69		VCAM1_HUMAN (107-363): 1.98e-19: 93.3: 18.02
+	Hs
		924597 GRB2_HUMAN (1-123): 1.97e-35: 122: 19.69		MYLK_HUMAN (248-338): 2.37e-17: 87.5: 20.20
+	Hs
		434019 LYN_HUMAN (1-125): 1.04e-39: 140: 19.85		ROBO2_HUMAN (20-294): 4.48e-11: 67.4: 9.66