HitPredict

Interactor 1: DNJA2 (O60884)
DnaJ homolog subfamily A member 2 (Cell cycle progression restoration gene 3 protein) (Dnj3) (Dj3) (HIRA-interacting protein 4) (Renal carcinoma antigen NY-REN-14)
Gene: DNAJA2

Interactor 2: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	27483141, 33731348
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 412 Hs			1 595
+	Hs
		369065 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		ESR1_HUMAN (1-595): 0: 599: 100.00
+	Hs
		370182 DNJA3_HUMAN (2-395): 9.05e-116: 348: 26.72		ESR1_HUMAN (1-595): 0: 599: 100.00
+	Hs
		370632 DNJB4_HUMAN (6-358): 4.06e-118: 348: 33.05		ESR1_HUMAN (1-595): 0: 599: 100.00
+	Hs
		370625 DJB11_HUMAN (2-355): 1.66e-108: 325: 35.85		ESR1_HUMAN (1-595): 0: 599: 100.00
+	Hs
		243232 DNJA2_HUMAN (1-412): 1.22e-168: 480: 100.00		ERR2_HUMAN (92-547): 4.3e-116: 354: 34.86
+	Hs
		243248 DNJA2_HUMAN (1-412): 1.22e-168: 480: 100.00		GCR_HUMAN (5-557): 4.67e-109: 346: 22.51
+	Rn
		193490 DNJA2_RAT (1-412): 2.8e-167: 476: 99.03		GCR_RAT (5-557): 9.7e-106: 338: 22.68
+	Hs
		320175 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		ERR2_HUMAN (92-547): 4.3e-116: 354: 34.86
+	Rn
		415138 DNJA1_RAT (4-410): 6.52e-154: 442: 54.52		GCR_RAT (5-557): 9.7e-106: 338: 22.68
+	Hs
		369012 DNJB1_HUMAN (10-356): 4.98e-50: 174: 36.49		ESR1_HUMAN (1-595): 0: 599: 100.00
+	Hs
		681353 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		PPARG_HUMAN (55-546): 2.12e-100: 316: 20.35
+	Hs
		1269841 DNJB4_HUMAN (6-358): 4.06e-118: 348: 33.05		ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88
+	Mm
		1142715 DNJA3_MOUSE (2-395): 4.22e-117: 351: 25.98		ERR2_MOUSE (92-547): 6.98e-113: 345: 34.42
+	Hs
		377774 DJB11_HUMAN (2-355): 1.66e-108: 325: 35.85		GCR_HUMAN (5-557): 4.67e-109: 346: 22.51
+	Hs
		740581 DNJA3_HUMAN (2-395): 9.05e-116: 348: 26.72		PPARG_HUMAN (55-546): 2.12e-100: 316: 20.35
+	Hs
		414448 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		PRGR_HUMAN (183-508): 6.92e-44: 170: 32.14
+	Hs
		487169 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		ANDR_HUMAN (172-455): 8.95e-37: 148: 30.16
+	Hs
		636387 DNJB1_HUMAN (10-356): 4.98e-50: 174: 36.49		ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88