HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 0.60 0.721

The method score is based on:

Property Details
Experiments 29172540, 31239290, 32416067, 30554943, 35987950, 24403256
Identification Methods affinity chromatography technology, proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0002039 - p53 binding
GO:0003682 - chromatin binding
GO:0005634 - nucleus
and 6 others

more...
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 1362
Hs

1 393
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+ Dm
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024