HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	32416067, 37827155
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006974 - DNA damage response
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1362 Hs			1 616
+	Hs
		651853 KAT2B_HUMAN (327-456): 5.61e-22: 105: 26.92		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		651852 KAT2A_HUMAN (327-456): 1.76e-20: 100: 26.15		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		651796 PHIP_HUMAN (26-669): 5.56e-18: 92.9: 13.30		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		651064 BPTF_HUMAN (67-161): 9.86e-11: 68.9: 41.05		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Sc
		607253 BDF1_YEAST (7-303): 2.12e-26: 118: 17.85		RFA1_YEAST (4-615): 0: 596: 31.69