HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: VHL (P40337)
von Hippel-Lindau disease tumor suppressor (Protein G7) (pVHL)
Gene: VHL

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	1.00	0.812

Property	Details
Experiments	33567268, 37919549
Identification Methods	enzymatic study, affinity chromatography technology, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Bromodomain~VHL
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0019899 - enzyme binding GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 1362 Hs			1 213
+	Hs
		772088 KAT2B_HUMAN (327-456): 5.61e-22: 105: 26.92		VHL_HUMAN (1-213): 3.45e-146: 407: 100.00
+	Hs
		772087 KAT2A_HUMAN (327-456): 1.76e-20: 100: 26.15		VHL_HUMAN (1-213): 3.45e-146: 407: 100.00
+	Hs
		772082 PHIP_HUMAN (26-669): 5.56e-18: 92.9: 13.30		VHL_HUMAN (1-213): 3.45e-146: 407: 100.00