HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: CRK (P46108)
Adapter molecule crk (Proto-oncogene c-Crk) (p38)
Gene: CRK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	32416067, 17474147
Identification Methods	affinity chromatography technology, peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1362 Hs			1 304
+	Hs
		244252 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67
+	Hs
		243880 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		NCK1_HUMAN (2-100): 1.55e-10: 63.3: 18.00
+	Hs
		631392 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67
+	Hs
		855801 BRDT_HUMAN (26-339): 2.9e-26: 119: 19.24		VAV2_HUMAN (2-191): 3.44e-29: 119: 19.74
+	Hs
		557751 PHIP_HUMAN (26-669): 5.56e-18: 92.9: 13.30		NCK1_HUMAN (2-100): 1.55e-10: 63.3: 18.00