HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: SRSF6 (Q13247)
Serine/arginine-rich splicing factor 6 (Pre-mRNA-splicing factor SRP55) (Splicing factor, arginine/serine-rich 6)
Gene: SRSF6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31239290, 35987950
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1362 Hs			1 344
+	Hs
		244340 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65
+	Hs
		244886 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		RBM4_HUMAN (1-343): 1.17e-47: 166: 17.05
+	Hs
		244380 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		SRSF9_HUMAN (3-222): 5.6e-49: 165: 34.22
+	Hs
		243851 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		PABP1_HUMAN (101-191): 1.28e-11: 67.6: 19.79
+	Hs
		244283 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		SRSF3_HUMAN (3-78): 2.4e-09: 57.4: 46.84
+	Hs
		992783 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65
+	Hs
		631419 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		SRSF9_HUMAN (3-222): 5.6e-49: 165: 34.22
+	Hs
		1028552 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		SRSF9_HUMAN (3-222): 5.6e-49: 165: 34.22
+	Zm
		19361 A0A1D6HCG5_MAIZE (43-242): 1.58e-37: 153: 25.00		Q64HC3_MAIZE (4-281): 4.97e-49: 167: 37.41
+	Hs
		1028563 BRDT_HUMAN (26-339): 2.9e-26: 119: 19.24		SRSF9_HUMAN (3-222): 5.6e-49: 165: 34.22
+	Sc
		965476 GCN5_YEAST (140-462): 1.42e-41: 161: 16.37		NOP3_YEAST (3-326): 1.19e-19: 91.2: 19.94
+	Sc
		715372 SPT7_YEAST (223-610): 3.64e-27: 122: 12.08		NOP3_YEAST (3-326): 1.19e-19: 91.2: 19.94