HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: HNRPD (Q14103)
Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1)
Gene: HNRNPD

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31239290, 35987950
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045893 - positive regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1362 Hs			1 355
+	Hs
		161910 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		HNRDL_HUMAN (89-355): 3.71e-56: 190: 62.63
+	Hs
		244842 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		ROAA_HUMAN (30-355): 3.41e-55: 185: 53.89
+	Hs
		244148 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		ROA3_HUMAN (64-265): 2.66e-50: 174: 37.02
+	Hs
		243851 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		PABP1_HUMAN (88-272): 2.1e-42: 157: 16.93
+	Hs
		243935 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		ROA2_HUMAN (98-277): 8.38e-39: 142: 41.40
+	Hs
		243831 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		ROA1_HUMAN (63-177): 4.79e-20: 92: 26.83
+	Hs
		201645 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		MSI1H_HUMAN (21-180): 2.38e-16: 81: 28.13
+	Hs
		1048158 KAT2B_HUMAN (327-456): 5.61e-22: 105: 26.92		HNRPD_HUMAN (1-355): 9.1e-72: 229: 100.00
+	Hs
		201647 BRD1_HUMAN (197-781): 8.89e-33: 140: 13.99		MSI1H_HUMAN (21-180): 2.38e-16: 81: 28.13