HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: NUMA1 (Q14980)
Nuclear mitotic apparatus protein 1 (Nuclear matrix protein-22) (NMP-22) (Nuclear mitotic apparatus protein) (NuMA protein) (SP-H antigen)
Gene: NUMA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.676

Property	Details
Experiments	31239290, 32416067, 30554943, 35987950
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005694 - chromosome
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1362 Hs			1 2115
+	Hs
		631429 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00
+	Hs
		1061116 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00
+	Hs
		319199 BRD1_HUMAN (197-781): 8.89e-33: 140: 13.99		NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00
+	Hs
		1061132 BRDT_HUMAN (26-339): 2.9e-26: 119: 19.24		NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00
+	Hs
		1061156 PB1_HUMAN (26-956): 2.35e-19: 97.1: 10.81		NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00
+	Hs
		1061186 PHIP_HUMAN (26-669): 5.56e-18: 92.9: 13.30		NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00
+	Hs
		244551 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		CROCC_HUMAN (1-1268): 5.14e-34: 146: 13.75
+	Hs
		244025 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62
+	Hs
		244026 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		MYH10_HUMAN (1281-2075): 5.26e-33: 142: 12.34
+	Hs
		244466 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		PLEC_HUMAN (45-1230): 3.46e-32: 140: 13.37
+	Hs
		243855 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		TPR_HUMAN (2-620): 2.42e-18: 94.7: 12.04
+	Hs
		631458 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		CROCC_HUMAN (1-1268): 5.14e-34: 146: 13.75
+	Hs
		1271492 KAT2B_HUMAN (327-456): 5.61e-22: 105: 26.92		CP250_HUMAN (1-1659): 6.01e-59: 228: 13.08
+	Hs
		319112 BRD1_HUMAN (197-781): 8.89e-33: 140: 13.99		MYH6_HUMAN (1-883): 5.66e-32: 139: 13.37
+	Hs
		1123369 BRDT_HUMAN (26-339): 2.9e-26: 119: 19.24		CROCC_HUMAN (1-1268): 5.14e-34: 146: 13.75
+	Hs
		518903 PHIP_HUMAN (26-669): 5.56e-18: 92.9: 13.30		TPR_HUMAN (2-620): 2.42e-18: 94.7: 12.04