HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: NONO (Q15233)
Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit)
Gene: NONO

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31239290, 35987950
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005694 - chromosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1362 Hs			1 471
+	Hs
		244707 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		PSPC1_HUMAN (20-470): 2.17e-67: 226: 58.41
+	Hs
		243851 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89
+	Hs
		243939 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		SFPQ_HUMAN (45-471): 3.15e-53: 192: 56.92
+	Hs
		244491 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		ELAV1_HUMAN (68-205): 7.38e-47: 166: 27.82
+	Hs
		244886 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		RBM4_HUMAN (75-182): 7.64e-09: 59.3: 35.71
+	Rn
		1117315 Q6AYL3_RAT (336-590): 5.88e-18: 88.6: 22.75		Q4KM71_RAT (23-471): 1.85e-54: 195: 55.72
+	Rn
		78192 Q6AYL3_RAT (336-590): 5.88e-18: 88.6: 22.75		ELAV1_RAT (68-205): 2.05e-46: 165: 28.48