Interactor 1: MGRN1 (O60291)
E3 ubiquitin-protein ligase MGRN1 (EC 2.3.2.27) (Mahogunin RING finger protein 1) (RING finger protein 156) (RING-type E3 ubiquitin transferase MGRN1)
Gene: MGRN1
Interactor 2: TS101 (Q99816)
Tumor susceptibility gene 101 protein (ESCRT-I complex subunit TSG101)
Gene: TSG101
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.88 | 0.60 | 0.729 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 17229889, 19703557, 25416956, 37219487, 19549727 |
| Identification Methods | pull down, enzymatic study, affinity chromatography technology, two hybrid, unspecified method, validated two hybrid, two hybrid prey pooling approach, two hybrid array, phage display |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005737 - cytoplasm GO:0005769 - early endosome GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0008333 - endosome to lysosome transport and 1 others more... |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
