HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: NEDD8 (Q15843)
NEDD8 (Neddylin) (Neural precursor cell expressed developmentally down-regulated protein 8) (NEDD-8) (Ubiquitin-like protein Nedd8)
Gene: NEDD8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	32416067, 33567268
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1362 Hs			1 81
+	Hs
		244251 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		RS27A_HUMAN (1-77): 6.66e-37: 122: 57.14
+	Sc
		408449 GCN5_YEAST (140-462): 1.42e-41: 161: 16.37		RS31_YEAST (1-70): 3.03e-30: 105: 52.86
+	Sc
		408321 SPT7_YEAST (223-610): 3.64e-27: 122: 12.08		RS31_YEAST (1-70): 3.03e-30: 105: 52.86
+	Sc
		408323 BDF1_YEAST (7-303): 2.12e-26: 118: 17.85		RS31_YEAST (1-70): 3.03e-30: 105: 52.86
+	Hs
		1079551 PHIP_HUMAN (26-669): 5.56e-18: 92.9: 13.30		NEDD8_HUMAN (1-81): 2.07e-30: 103: 100.00