HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: H32 (Q71DI3)
Histone H3.2 (H3-clustered histone 13) (H3-clustered histone 14) (H3-clustered histone 15) (Histone H3/m) (Histone H3/o)
Gene: H3C15

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	31239290, 18500820
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1362 Hs			1 136
+	Hs
		244266 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		244284 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		631395 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		934782 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		631400 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		952348 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		631374 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		CENPA_HUMAN (9-133): 2.85e-44: 143: 50.00
+	Hs
		828234 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		CENPA_HUMAN (9-133): 2.85e-44: 143: 50.00
+	Sp
		457192 GCN5_SCHPO (143-461): 4.74e-40: 157: 14.11		H31_SCHPO (1-136): 2.22e-59: 181: 91.91
+	Sc
		860437 RSC1_YEAST (87-841): 2.12e-39: 161: 12.50		H3_YEAST (1-136): 7.77e-56: 172: 88.97
+	Sc
		902028 GCN5_YEAST (140-462): 1.42e-41: 161: 16.37		H3_YEAST (1-136): 7.77e-56: 172: 88.97
+	Sc
		902084 RSC2_YEAST (87-766): 1.06e-38: 159: 13.49		H3_YEAST (1-136): 7.77e-56: 172: 88.97
+	Hs
		319165 BRD1_HUMAN (197-781): 8.89e-33: 140: 13.99		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Sp
		457186 YK82_SCHPO (49-215): 1.43e-35: 147: 26.35		H31_SCHPO (1-136): 2.22e-59: 181: 91.91
+	Hs
		319213 BRD1_HUMAN (197-781): 8.89e-33: 140: 13.99		H31T_HUMAN (1-136): 8.3e-62: 187: 96.32
+	Hs
		319169 BRD1_HUMAN (197-781): 8.89e-33: 140: 13.99		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		319242 BRD1_HUMAN (197-781): 8.89e-33: 140: 13.99		H32_HUMAN (1-136): 3.73e-61: 186: 100.00
+	At
		886669 GTE3_ARATH (251-640): 4.07e-33: 136: 17.38		H31_ARATH (1-136): 9.88e-61: 184: 97.06
+	Dm
		356065 FSH_DROME (320-483): 8.28e-29: 128: 33.13		H3_DROME (1-136): 3.73e-61: 186: 100.00
+	Sc
		730923 RSC2_YEAST (87-766): 1.06e-38: 159: 13.49		CENPA_YEAST (18-134): 1.58e-41: 139: 56.67