HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: H2B1H (Q93079)
Histone H2B type 1-H (H2B-clustered histone 9) (Histone H2B.j) (H2B/j)
Gene: H2BC9

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34349018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0019899 - enzyme binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1362 Hs			1 126
+	Hs
		243805 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		H2B1J_HUMAN (1-126): 7.3e-55: 169: 97.62
+	Hs
		244513 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		H2B2E_HUMAN (1-126): 5.74e-55: 169: 98.41
+	Hs
		241395 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		H2B1K_HUMAN (1-126): 1.18e-54: 168: 98.41
+	Hs
		244011 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		H2B1B_HUMAN (1-126): 1.44e-54: 168: 96.83
+	Hs
		244236 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		H2B1C_HUMAN (1-126): 1.07e-54: 168: 99.21
+	Hs
		244660 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		H2B3B_HUMAN (1-126): 1.45e-52: 163: 96.03
+	Hs
		631445 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		H2B2E_HUMAN (1-126): 5.74e-55: 169: 98.41
+	Hs
		1066994 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		H2B2F_HUMAN (1-126): 1.7e-55: 170: 99.21
+	Hs
		631358 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		H2B1B_HUMAN (1-126): 1.44e-54: 168: 96.83
+	Hs
		631389 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		H2B1C_HUMAN (1-126): 1.07e-54: 168: 99.21
+	Hs
		707639 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		H2B1B_HUMAN (1-126): 1.44e-54: 168: 96.83
+	Hs
		918378 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		H2B1C_HUMAN (1-126): 1.07e-54: 168: 99.21
+	Hs
		319121 BRD1_HUMAN (197-781): 8.89e-33: 140: 13.99		H2B1O_HUMAN (1-126): 2.36e-55: 170: 99.21
+	Sc
		355953 RSC1_YEAST (87-841): 2.12e-39: 161: 12.50		H2B2_YEAST (3-125): 4.15e-41: 134: 71.55
+	Sc
		355988 GCN5_YEAST (140-462): 1.42e-41: 161: 16.37		H2B2_YEAST (3-125): 4.15e-41: 134: 71.55
+	Sc
		356020 RSC2_YEAST (87-766): 1.06e-38: 159: 13.49		H2B2_YEAST (3-125): 4.15e-41: 134: 71.55
+	Sp
		392629 YK82_SCHPO (49-215): 1.43e-35: 147: 26.35		H2B1_SCHPO (4-125): 6.05e-46: 146: 70.49
+	Sc
		355564 RSC1_YEAST (87-841): 2.12e-39: 161: 12.50		H2B1_YEAST (4-125): 8.17e-37: 123: 72.13
+	Sc
		355611 GCN5_YEAST (140-462): 1.42e-41: 161: 16.37		H2B1_YEAST (4-125): 8.17e-37: 123: 72.13
+	Sc
		355655 RSC2_YEAST (87-766): 1.06e-38: 159: 13.49		H2B1_YEAST (4-125): 8.17e-37: 123: 72.13