HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: ATAD5 (Q96QE3)
ATPase family AAA domain-containing protein 5 (Chromosome fragility-associated gene 1 protein)
Gene: ATAD5

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	0.60	0.730

Property	Details
Experiments	31753913, 32416067, 33961781, 30554943, 21555454, 24981860
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1362 Hs			1 1844
+	Hs
		631555 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		ATAD5_HUMAN (1-1844): 0: 1306: 100.00
+	Hs
		1067104 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		ATAD5_HUMAN (1-1844): 0: 1306: 100.00
+	Hs
		244571 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		NIPBL_HUMAN (66-837): 6.64e-54: 211: 12.10
+	Hs
		244023 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		RFC1_HUMAN (433-1276): 4.59e-53: 207: 14.77
+	Hs
		244697 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		CTF18_HUMAN (998-1222): 2.17e-34: 146: 17.57
+	Hs
		244438 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		MDC1_HUMAN (10-849): 1.46e-20: 101: 8.33
+	Hs
		244078 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		ATRX_HUMAN (88-1036): 2.62e-11: 71.5: 13.08
+	Hs
		1067006 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		NIPBL_HUMAN (66-837): 6.64e-54: 211: 12.10
+	Hs
		631361 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		RFC1_HUMAN (433-1276): 4.59e-53: 207: 14.77
+	Hs
		722244 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		RFC1_HUMAN (433-1276): 4.59e-53: 207: 14.77
+	Hs
		631425 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		MDC1_HUMAN (10-849): 1.46e-20: 101: 8.33
+	Hs
		1056838 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		MDC1_HUMAN (10-849): 1.46e-20: 101: 8.33
+	Dm
		113976 M9PB30_DROME (168-975): 2.55e-17: 90.9: 12.03		M9PB30_DROME (11-756): 8.28e-30: 132: 6.94
+	Hs
		319166 BRD1_HUMAN (197-781): 8.89e-33: 140: 13.99		MAP1A_HUMAN (6-1227): 4.21e-11: 70.7: 7.00