HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: ASXL3 (Q9C0F0)
Putative Polycomb group protein ASXL3 (Additional sex combs-like protein 3)
Gene: ASXL3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	32669118, 34536441
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1362 Hs			1 2248
+	Hs
		244596 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		ASXL2_HUMAN (1196-2248): 2.48e-54: 212: 12.78
+	Hs
		244645 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		ASXL1_HUMAN (1104-2248): 2.83e-43: 176: 13.52
+	Hs
		244438 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		MDC1_HUMAN (402-1995): 1.05e-22: 109: 10.74
+	Hs
		319166 BRD1_HUMAN (197-781): 8.89e-33: 140: 13.99		MAP1A_HUMAN (5-2125): 2.22e-54: 213: 10.33
+	Hs
		1067200 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		SRRM2_HUMAN (548-2180): 2.16e-27: 125: 10.23
+	Hs
		631425 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		MDC1_HUMAN (402-1995): 1.05e-22: 109: 10.74
+	Hs
		1056838 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		MDC1_HUMAN (402-1995): 1.05e-22: 109: 10.74
+	Hs
		1262846 PHIP_HUMAN (26-669): 5.56e-18: 92.9: 13.30		SRRM2_HUMAN (548-2180): 2.16e-27: 125: 10.23
+	Hs
		257668 PHIP_HUMAN (26-669): 5.56e-18: 92.9: 13.30		ANR17_HUMAN (345-1422): 1.78e-26: 121: 11.40
+	Dm
		113976 M9PB30_DROME (168-975): 2.55e-17: 90.9: 12.03		M9PB30_DROME (1371-2237): 8.6e-23: 109: 8.95