HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: SKI8 (Q9GZS3)
Superkiller complex protein 8 (Ski8) (Meiotic recombination REC14 protein homolog) (WD repeat-containing protein 61) [Cleaved into: Superkiller complex protein 8, N-terminally processed (WD repeat-containing protein 61, N-terminally processed)]
Gene: SKIC8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32416067
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1362 Hs			1 305
+	Hs
		244767 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		SNR40_HUMAN (2-216): 4.5e-59: 194: 22.42
+	Hs
		209361 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		PLRG1_HUMAN (4-217): 2.47e-43: 156: 22.52
+	Hs
		244210 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		WDR5_HUMAN (179-304): 4.63e-41: 147: 33.33
+	Hs
		196921 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		PRP4_HUMAN (218-304): 3.86e-14: 74.2: 13.68
+	Hs
		245095 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		WDR3_HUMAN (6-218): 4.82e-10: 62.4: 25.56
+	Hs
		244350 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		TBL3_HUMAN (151-265): 1.22e-09: 61.2: 28.93
+	Hs
		631541 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		FBXW7_HUMAN (91-303): 1.6e-63: 214: 24.30
+	Hs
		196957 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		PRP4_HUMAN (218-304): 3.86e-14: 74.2: 13.68
+	Sp
		252179 YK82_SCHPO (49-215): 1.43e-35: 147: 26.35		NLE1_SCHPO (181-305): 1.86e-34: 132: 23.88
+	Hs
		1016281 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		TBL3_HUMAN (151-265): 1.22e-09: 61.2: 28.93
+	Mm
		903669 KMT2C_MOUSE (495-1183): 4.41e-22: 106: 13.55		WDR5_MOUSE (179-304): 4.63e-41: 147: 33.33
+	Hs
		903409 KAT2B_HUMAN (327-456): 5.61e-22: 105: 26.92		WDR5_HUMAN (179-304): 4.63e-41: 147: 33.33
+	Hs
		903408 KAT2A_HUMAN (327-456): 1.76e-20: 100: 26.15		WDR5_HUMAN (179-304): 4.63e-41: 147: 33.33
+	Dm
		1358857 Q9VTZ1_DROME (336-457): 5.41e-22: 105: 30.89		WDS_DROME (2-95): 1.13e-16: 81.2: 21.88
+	Hs
		267784 KAT2B_HUMAN (327-456): 5.61e-22: 105: 26.92		TAF5L_HUMAN (24-208): 1.33e-09: 60.8: 25.76
+	Hs
		267783 KAT2A_HUMAN (327-456): 1.76e-20: 100: 26.15		TAF5L_HUMAN (24-208): 1.33e-09: 60.8: 25.76