HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: UBE2T (Q9NPD8)
Ubiquitin-conjugating enzyme E2 T (EC 2.3.2.23) (Cell proliferation-inducing gene 50 protein) (E2 ubiquitin-conjugating enzyme T) (Ubiquitin carrier protein T) (Ubiquitin-protein ligase T)
Gene: UBE2T

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	32416067, 35987950
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006974 - DNA damage response
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1362 Hs			1 197
+	Hs
		244239 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		UB2D2_HUMAN (2-152): 1.52e-76: 227: 41.72
+	Hs
		244199 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		UBE2N_HUMAN (4-152): 1.1e-70: 213: 44.97
+	Hs
		244756 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		UB2E3_HUMAN (3-152): 1.45e-68: 209: 40.00
+	Hs
		244147 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		UB2E1_HUMAN (3-152): 1.27e-67: 206: 40.00
+	Hs
		244107 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		UBE2A_HUMAN (3-149): 1.89e-66: 202: 34.01
+	Hs
		849391 KAT2B_HUMAN (327-456): 5.61e-22: 105: 26.92		UB2D1_HUMAN (2-152): 1.05e-76: 228: 41.72
+	Hs
		919805 KAT2B_HUMAN (327-456): 5.61e-22: 105: 26.92		UB2D2_HUMAN (2-152): 1.52e-76: 227: 41.72
+	Hs
		895863 KAT2B_HUMAN (327-456): 5.61e-22: 105: 26.92		UB2D3_HUMAN (2-152): 2.48e-75: 224: 41.06