Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: MED16 (Q9Y2X0)
Mediator of RNA polymerase II transcription subunit 16 (Mediator complex subunit 16) (Thyroid hormone receptor-associated protein 5) (Thyroid hormone receptor-associated protein complex 95 kDa component) (Trap95) (Vitamin D3 receptor-interacting protein complex 92 kDa component) (DRIP92)
Gene: MED16

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 0.60 0.640

The method score is based on:

Property Details
Experiments 32416067, 33567268, 30554943
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0032968 - positive regulation of transcription elongation by RNA polymerase II
and 1 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 1362
Hs

1 877
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024