HitPredict

Interactor 1: PFD1 (O60925)
Prefoldin subunit 1
Gene: PFDN1

Interactor 2: PFD2 (Q9UHV9)
Prefoldin subunit 2
Gene: PFDN2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	1.00	0.920

The method score is based on:

Property	Details
Experiments	28514442, 33961781, 24981860, 34349018, 16876117
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation, two hybrid
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	Prefoldin_2~Prefoldin_2
Common GO terms	GO:0001540 - amyloid-beta binding GO:0005737 - cytoplasm GO:0006457 - protein folding GO:0016272 - prefoldin complex GO:0044183 - protein folding chaperone and 3 others more... GO:0051082 - unfolded protein binding GO:0061077 - chaperone-mediated protein folding GO:1905907 - negative regulation of amyloid fibril formation
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	122
Hs

1	154

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024