HitPredict

Interactor 1: NBN (O60934)
Nibrin (Cell cycle regulatory protein p95) (Nijmegen breakage syndrome protein 1) (hNbs1)
Gene: NBN

Interactor 2: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.55	0.619

The method score is based on:

Property	Details
Experiments	32807901, 35140242, 38580884
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005657 - replication fork GO:0005730 - nucleolus GO:0005829 - cytosol and 7 others more... GO:0006302 - double-strand break repair GO:0007405 - neuroblast proliferation GO:0016605 - PML body GO:0030330 - DNA damage response, signal transduction by p53 class mediator GO:0035861 - site of double-strand break GO:0051726 - regulation of cell cycle GO:0097193 - intrinsic apoptotic signaling pathway
Homologous interactions	0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024