Interactor 1: NBN (O60934)
Nibrin (Cell cycle regulatory protein p95) (Nijmegen breakage syndrome protein 1) (hNbs1)
Gene: NBN

Interactor 2: MRE11 (P49959)
Double-strand break repair protein MRE11 (EC 3.1.-.-) (Meiotic recombination 11 homolog 1) (MRE11 homolog 1) (Meiotic recombination 11 homolog A) (MRE11 homolog A)
Gene: MRE11

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 0.60 0.770

The method score is based on:

Property Details
Experiments 23530059, 10783165, 12679336, 30440001, 30179224, 11062235, 22941933, 18458108, 11238951, 17526493, 34348893, 16982765, 17429352, 36736531, 23912341, 12607003, 12447395, 19244116, 21884979, 15758953 and 20 others

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Identification Methods affinity chromatography technology, biochemical, two hybrid, pull down, anti bait coimmunoprecipitation, tandem affinity purification, coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000723 - telomere maintenance
GO:0000724 - double-strand break repair via homologous recombination
GO:0000729 - DNA double-strand break processing
GO:0000781 - chromosome, telomeric region
GO:0005634 - nucleus
and 19 others

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Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 754
Hs

1 708
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024