HitPredict

Interactor 1: NBN (O60934)
Nibrin (Cell cycle regulatory protein p95) (Nijmegen breakage syndrome protein 1) (hNbs1)
Gene: NBN

Interactor 2: TP53B (Q12888)
TP53-binding protein 1 (53BP1) (p53-binding protein 1) (p53BP1)
Gene: TP53BP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

The method score is based on:

Property	Details
Experiments	29656893, 20010693
Identification Methods	proximity labelling technology, pull down, affinity chromatography technology
Interaction Type	physical association, direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000077 - DNA damage checkpoint signaling GO:0000781 - chromosome, telomeric region GO:0003684 - damaged DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm and 4 others more... GO:0005657 - replication fork GO:0035861 - site of double-strand break GO:0042393 - histone binding GO:1990166 - protein localization to site of double-strand break
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	754
Hs

1	1972

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024