Interactor 1: NBN (O60934)
Nibrin (Cell cycle regulatory protein p95) (Nijmegen breakage syndrome protein 1) (hNbs1)
Gene: NBN

Interactor 2: RAD50 (Q92878)
DNA repair protein RAD50 (hRAD50) (EC 3.6.-.-)
Gene: RAD50

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 0.60 0.766

The method score is based on:

Property Details
Experiments 23530059, 26215093, 11062235, 12124328, 9705271, 34348893, 16982765, 22833675, 23912341, 12607003, 17500065, 16391231, 15734743, 10783165, 12679336, 30440001, 30179224, 22941933, 24981860, 11238951 and 7 others

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Identification Methods affinity chromatography technology, biochemical, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000723 - telomere maintenance
GO:0000724 - double-strand break repair via homologous recombination
GO:0000729 - DNA double-strand break processing
GO:0000781 - chromosome, telomeric region
GO:0005634 - nucleus
and 17 others

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Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 754
Hs

1 1312
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024