HitPredict

Interactor 1: NBN (O60934)
Nibrin (Cell cycle regulatory protein p95) (Nijmegen breakage syndrome protein 1) (hNbs1)
Gene: NBN

Interactor 2: UBE2O (Q9C0C9)
(E3-independent) E2 ubiquitin-conjugating enzyme (EC 2.3.2.24) (E2/E3 hybrid ubiquitin-protein ligase UBE2O) (Ubiquitin carrier protein O) (Ubiquitin-conjugating enzyme E2 O) (Ubiquitin-conjugating enzyme E2 of 230 kDa) (Ubiquitin-conjugating enzyme E2-230K) (Ubiquitin-protein ligase O)
Gene: UBE2O

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34921745
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0070534 - protein K63-linked ubiquitination
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 754 Hs			1 1292
+	Hs
		246194 NBN_HUMAN (1-754): 0: 1078: 100.00		UB2D1_HUMAN (953-1106): 1.82e-61: 208: 19.11
+	Hs
		246199 NBN_HUMAN (1-754): 0: 1078: 100.00		UBE2N_HUMAN (956-1103): 1.44e-45: 163: 22.52
+	Hs
		246190 NBN_HUMAN (1-754): 0: 1078: 100.00		UBE2A_HUMAN (956-1112): 5.42e-42: 152: 26.75
+	Hs
		246204 NBN_HUMAN (1-754): 0: 1078: 100.00		UBE2B_HUMAN (956-1112): 2.98e-41: 150: 27.39