HitPredict

Interactor 1: SCN2B (O60939)
Sodium channel subunit beta-2
Gene: SCN2B

Interactor 2: PTPRF (P10586)
Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) (Leukocyte common antigen related) (LAR)
Gene: PTPRF

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	V-set~fn3, I-set~V-set
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 1907
+	Hs
		246337 SCN2B_HUMAN (1-215): 2.15e-75: 228: 100.00		PTPRD_HUMAN (29-1907): 0: 1573: 69.46
+	Hs
		489973 TIGIT_HUMAN (23-191): 1.5e-26: 104: 19.53		PTPRF_HUMAN (1-1907): 0: 1662: 100.00
+	Hs
		616977 TIGIT_HUMAN (23-191): 1.5e-26: 104: 19.53		PTPRD_HUMAN (29-1907): 0: 1573: 69.46
+	Rn
		873519 SCN2B_RAT (1-215): 1.06e-72: 221: 93.02		PTPRZ_RAT (1315-1623): 2.9e-46: 186: 24.53
+	Rn
		962614 SCN1B_RAT (13-185): 1.66e-31: 115: 20.22		PTPRZ_RAT (1315-1623): 2.9e-46: 186: 24.53
+	Hs
		441168 CD79A_HUMAN (6-214): 7.18e-28: 106: 19.82		PTPRC_HUMAN (362-695): 1.66e-10: 68.5: 14.29