HitPredict

Interactor 1: DTNB (O60941)
Dystrobrevin beta (DTN-B) (Beta-dystrobrevin)
Gene: DTNB

Interactor 2: SNTA1 (Q13424)
Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin-1)
Gene: SNTA1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.614

Property	Details
Experiments	10747910, 33961781
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 627 Hs			1 505
+	Mm
		251081 DTNB_MOUSE (1-623): 0: 787: 93.11		Q3UVD6_MOUSE (1-505): 3.51e-176: 506: 92.08
+	Hs
		246442 DTNB_HUMAN (1-627): 0: 795: 100.00		SNTB1_HUMAN (8-505): 9.95e-157: 458: 47.62
+	Mm
		251087 DTNB_MOUSE (1-623): 0: 787: 93.11		SNTB1_MOUSE (8-505): 5.72e-156: 456: 48.10
+	Mm
		251082 DTNB_MOUSE (1-623): 0: 787: 93.11		SNTB2_MOUSE (1-504): 3.01e-155: 454: 46.11
+	Hs
		246440 DTNB_HUMAN (1-627): 0: 795: 100.00		SNTB2_HUMAN (3-504): 3.86e-150: 441: 45.28
+	Mm
		1113338 DTNA_MOUSE (1-626): 0: 708: 70.41		Q3UVD6_MOUSE (1-505): 3.51e-176: 506: 92.08
+	Mm
		57297 DTNA_MOUSE (1-626): 0: 708: 70.41		A2AKD7_MOUSE (1-505): 3.43e-176: 506: 92.28
+	Mm
		1142419 DTNA_MOUSE (1-626): 0: 708: 70.41		SNTA1_MOUSE (1-505): 3.16e-173: 499: 91.55
+	Hs
		1033863 DTNA_HUMAN (1-626): 0: 692: 70.09		SNTA1_HUMAN (1-505): 2.08e-174: 502: 100.00
+	Mm
		1307817 DTNA_MOUSE (1-626): 0: 708: 70.41		SNTB1_MOUSE (8-505): 5.72e-156: 456: 48.10
+	Mm
		1142424 DTNA_MOUSE (1-626): 0: 708: 70.41		SNTB2_MOUSE (1-504): 3.01e-155: 454: 46.11
+	Hs
		246499 DTNB_HUMAN (1-627): 0: 795: 100.00		SNTG1_HUMAN (77-501): 1.61e-113: 347: 26.04
+	Hs
		1033944 DTNA_HUMAN (1-626): 0: 692: 70.09		SNTB2_HUMAN (3-504): 3.86e-150: 441: 45.28
+	Hs
		246500 DTNB_HUMAN (1-627): 0: 795: 100.00		SNTG2_HUMAN (77-501): 8.81e-109: 335: 25.43
+	Mm
		251086 DTNB_MOUSE (1-623): 0: 787: 93.11		SNTG1_MOUSE (77-501): 1.57e-111: 341: 26.70
+	Mm
		251085 DTNB_MOUSE (1-623): 0: 787: 93.11		SNTG2_MOUSE (76-501): 4.24e-110: 339: 25.37
+	Mm
		1267816 DTNA_MOUSE (1-626): 0: 708: 70.41		SNTG1_MOUSE (77-501): 1.57e-111: 341: 26.70
+	Mm
		1267814 DTNA_MOUSE (1-626): 0: 708: 70.41		SNTG2_MOUSE (76-501): 4.24e-110: 339: 25.37
+	Hs
		246492 DTNB_HUMAN (1-627): 0: 795: 100.00		LIN7B_HUMAN (85-172): 7.84e-29: 114: 40.91
+	Mm
		250657 DTNA_MOUSE (1-626): 0: 708: 70.41		LNX1_MOUSE (1-319): 6.11e-22: 101: 14.60