HitPredict

Interactor 1: DTNB (O60941)
Dystrobrevin beta (DTN-B) (Beta-dystrobrevin)
Gene: DTNB

Interactor 2: SNTB2 (Q13425)
Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin-3) (SNT3) (Syntrophin-like) (SNTL)
Gene: SNTB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33961781, 24981860
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0045202 - synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 627 Hs			1 540
+	Mm
		251082 DTNB_MOUSE (1-623): 0: 787: 93.11		SNTB2_MOUSE (16-540): 1.09e-162: 474: 95.05
+	Hs
		246442 DTNB_HUMAN (1-627): 0: 795: 100.00		SNTB1_HUMAN (24-539): 2.43e-151: 445: 55.30
+	Mm
		251087 DTNB_MOUSE (1-623): 0: 787: 93.11		SNTB1_MOUSE (24-539): 6.08e-149: 439: 54.53
+	Hs
		246439 DTNB_HUMAN (1-627): 0: 795: 100.00		SNTA1_HUMAN (16-539): 1.35e-142: 422: 45.49
+	Mm
		251081 DTNB_MOUSE (1-623): 0: 787: 93.11		Q3UVD6_MOUSE (16-539): 1.47e-145: 429: 45.30
+	Mm
		1142424 DTNA_MOUSE (1-626): 0: 708: 70.41		SNTB2_MOUSE (16-540): 1.09e-162: 474: 95.05
+	Hs
		1033944 DTNA_HUMAN (1-626): 0: 692: 70.09		SNTB2_HUMAN (18-540): 1.13e-164: 480: 100.00
+	Mm
		1307817 DTNA_MOUSE (1-626): 0: 708: 70.41		SNTB1_MOUSE (24-539): 6.08e-149: 439: 54.53
+	Mm
		57297 DTNA_MOUSE (1-626): 0: 708: 70.41		A2AKD7_MOUSE (16-539): 1.22e-145: 430: 45.49
+	Hs
		1046461 DTNA_HUMAN (1-626): 0: 692: 70.09		SNTB1_HUMAN (24-539): 2.43e-151: 445: 55.30
+	Mm
		1113338 DTNA_MOUSE (1-626): 0: 708: 70.41		Q3UVD6_MOUSE (16-539): 1.47e-145: 429: 45.30
+	Hs
		246500 DTNB_HUMAN (1-627): 0: 795: 100.00		SNTG2_HUMAN (103-536): 2.07e-110: 341: 24.04
+	Mm
		251085 DTNB_MOUSE (1-623): 0: 787: 93.11		SNTG2_MOUSE (103-536): 1.54e-113: 349: 24.47
+	Mm
		1142419 DTNA_MOUSE (1-626): 0: 708: 70.41		SNTA1_MOUSE (16-539): 1.34e-142: 422: 45.15
+	Hs
		246499 DTNB_HUMAN (1-627): 0: 795: 100.00		SNTG1_HUMAN (103-536): 1.35e-108: 335: 22.66
+	Mm
		251086 DTNB_MOUSE (1-623): 0: 787: 93.11		SNTG1_MOUSE (103-536): 8.15e-106: 328: 22.56
+	Hs
		1033863 DTNA_HUMAN (1-626): 0: 692: 70.09		SNTA1_HUMAN (16-539): 1.35e-142: 422: 45.49
+	Mm
		1267814 DTNA_MOUSE (1-626): 0: 708: 70.41		SNTG2_MOUSE (103-536): 1.54e-113: 349: 24.47
+	Mm
		1267816 DTNA_MOUSE (1-626): 0: 708: 70.41		SNTG1_MOUSE (103-536): 8.15e-106: 328: 22.56
+	Hs
		246492 DTNB_HUMAN (1-627): 0: 795: 100.00		LIN7B_HUMAN (25-229): 4.57e-39: 143: 28.23