Interactor 1: MK38B (O61443)
Mitogen-activated protein kinase p38b (MAP kinase p38b) (MAPK p38b) (EC 2.7.11.24)
Gene: p38b

Interactor 2: MAPK2 (P49071)
MAP kinase-activated protein kinase 2 (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) (EC 2.7.11.1)
Gene: MAPk-Ak2

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.882

The method score is based on:

Property Details
Experiments 22801366, 21829386, 14605208, 22036573
Identification Methods affinity chromatography technology, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006468 - protein phosphorylation
GO:0009651 - response to salt stress
and 3 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 365
Dm

1 359
+ Dm
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ Mm
+ Hs
+ Hs
+ At
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024