Interactor 1: PYRE (O61790)
Orotate phosphoribosyltransferase (OPRT) (OPRTase) (EC 2.4.2.10) (Uracil phosphoribosyltransferase) (EC 2.4.2.9)
Gene: R12E2.11

Interactor 2: PYRE (O61790)
Orotate phosphoribosyltransferase (OPRT) (OPRTase) (EC 2.4.2.10) (Uracil phosphoribosyltransferase) (EC 2.4.2.9)
Gene: R12E2.11

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.723

The method score is based on:

Property Details
Experiments 19123269
Identification Methods two hybrid, two hybrid array, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pribosyltran~Pribosyltran
Common GO terms GO:0004588 - orotate phosphoribosyltransferase activity
GO:0004590 - orotidine-5'-phosphate decarboxylase activity
GO:0004845 - uracil phosphoribosyltransferase activity
GO:0006222 - UMP biosynthetic process
GO:0019856 - pyrimidine nucleobase biosynthetic process
and 2 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 227
Ce

1 227
+ Hs
+ Sp
+ Sc
+ Sc
+ At
+ At
+ At
+ Cj
+ At
+ At
+ At
+ Ec
+ Sp
+ Cj

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Last updated: 15 Jul 2024