Interactor 1: PRY1 (O62090)
Axin-like protein pry-1 (Protein polyray)
Gene: pry-1
Interactor 2: GSK3 (Q9U2Q9)
Glycogen synthase kinase-3 (EC 2.7.11.26)
Gene: gsk-3
Species: Caenorhabditis elegans
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.82 | 0.90 | 0.861 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12023307, 26780296, 17601533, unassigned1274 |
| Identification Methods | two hybrid, protein complementation assay, affinity chromatography technology, mammalian protein protein interaction trap, pull down |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Pkinase~RGS |
| Common GO terms | GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0032436 - positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0090090 - negative regulation of canonical Wnt signaling pathway |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
