HitPredict

Interactor 1: KLF2 (O62259)
Kruppel-like factor 2
Gene: klf-2

Interactor 2: Q7JP54 (Q7JP54)
NR LBD domain-containing protein
Gene: nhr-109

Species: Caenorhabditis elegans

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	23791784
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 299 Ce			1 318
+	Ce
		110414 KLF2_CAEEL (1-299): 1.68e-123: 356: 100.00		H2L0L6_CAEEL (8-318): 3.4e-75: 236: 98.71
+	Ce
		248112 KLF2_CAEEL (1-299): 1.68e-123: 356: 100.00		Q95QB3_CAEEL (8-318): 2.81e-73: 232: 57.63
+	Ce
		248113 KLF2_CAEEL (1-299): 1.68e-123: 356: 100.00		Q95Y07_CAEEL (8-313): 4.39e-73: 231: 31.05
+	Ce
		248107 KLF2_CAEEL (1-299): 1.68e-123: 356: 100.00		Q86PJ4_CAEEL (7-318): 3.18e-63: 207: 18.31
+	Ce
		248098 KLF2_CAEEL (1-299): 1.68e-123: 356: 100.00		Q3LQX0_CAEEL (7-318): 4.16e-55: 186: 18.85
+	Ce
		109539 KLF2_CAEEL (1-299): 1.68e-123: 356: 100.00		NHR66_CAEEL (16-314): 1.94e-51: 182: 16.58
+	Ce
		248076 KLF2_CAEEL (1-299): 1.68e-123: 356: 100.00		NHR22_CAEEL (54-317): 2.23e-51: 180: 17.16
+	Hs
		587168 KLF5_HUMAN (173-281): 1.12e-38: 143: 65.14		RXRA_HUMAN (8-316): 1.96e-74: 237: 15.81
+	Hs
		782683 ZN629_HUMAN (201-297): 6.74e-44: 161: 34.02		HNF4A_HUMAN (8-316): 5.86e-66: 216: 16.18
+	Hs
		1055261 ZN629_HUMAN (201-297): 6.74e-44: 161: 34.02		HNF4G_HUMAN (8-316): 2.08e-64: 210: 14.56
+	Hs
		434936 SP1_HUMAN (154-289): 9.91e-29: 117: 43.38		RXRA_HUMAN (8-316): 1.96e-74: 237: 15.81
+	Hs
		434909 SP1_HUMAN (154-289): 9.91e-29: 117: 43.38		COT1_HUMAN (8-315): 2.24e-67: 218: 11.69
+	Hs
		369571 KLF5_HUMAN (173-281): 1.12e-38: 143: 65.14		ESR1_HUMAN (10-316): 1.03e-54: 189: 12.80
+	Hs
		487967 KLF5_HUMAN (173-281): 1.12e-38: 143: 65.14		RARA_HUMAN (8-317): 4.1e-55: 187: 13.83
+	Hs
		204103 KLF4_HUMAN (177-280): 6.31e-37: 139: 65.39		ESR1_HUMAN (10-316): 1.03e-54: 189: 12.80
+	Rn
		1146024 Q66HP1_RAT (173-281): 1.06e-38: 141: 65.14		Q9QWJ1_RAT (8-317): 1e-53: 183: 13.83
+	Hs
		368935 ZN182_HUMAN (2-106): 3.65e-32: 127: 9.09		ESR1_HUMAN (10-316): 1.03e-54: 189: 12.80
+	Hs
		320156 SP1_HUMAN (154-289): 9.91e-29: 117: 43.38		ERR2_HUMAN (7-317): 2.71e-56: 189: 14.70
+	Hs
		368835 SP1_HUMAN (154-289): 9.91e-29: 117: 43.38		ESR1_HUMAN (10-316): 1.03e-54: 189: 12.80
+	Hs
		434908 SP1_HUMAN (154-289): 9.91e-29: 117: 43.38		RARA_HUMAN (8-317): 4.1e-55: 187: 13.83