Interactor 1: KCC2D (O62305)
Calcium/calmodulin-dependent protein kinase type II (CaM kinase II) (EC 2.7.11.17) (Uncoordinated protein 43)
Gene: unc-43

Interactor 2: MPK1 (P39745)
Mitogen-activated protein kinase mpk-1 (EC 2.7.11.24) (MAP kinase sur-1)
Gene: mpk-1

Species: Caenorhabditis elegans

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.847

The method score is based on:

Property Details
Experiments 12679813, 10615043, 14704431
Identification Methods two hybrid, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CaMKII_AD~Pkinase, Pkinase~Pkinase
Common GO terms GO:0000165 - MAPK cascade
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0016310 - phosphorylation
GO:0046872 - metal ion binding
and 1 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 720
Ce

1 444
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ Rn

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Last updated: 15 Jul 2024