Interactor 1: KCC2D (O62305)
Calcium/calmodulin-dependent protein kinase type II (CaM kinase II) (EC 2.7.11.17) (Uncoordinated protein 43)
Gene: unc-43

Interactor 2: PMK1 (Q17446)
Mitogen-activated protein kinase pmk-1 (EC 2.7.11.24) (Stress-activated protein kinase pmk-1) (p38 MAP kinase 1)
Gene: pmk-1

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.48 1.00 0.698

The method score is based on:

Property Details
Experiments 14704431
Identification Methods two hybrid, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CaMKII_AD~Pkinase, Pkinase~Pkinase
Common GO terms GO:0000165 - MAPK cascade
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0010628 - positive regulation of gene expression
GO:0046872 - metal ion binding
and 1 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 720
Ce

1 377
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ Rn
+ Hs

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Last updated: 15 Jul 2024