HitPredict

Interactor 1: MK38A (O62618)
Mitogen-activated protein kinase p38a (MAP kinase p38a) (MAPK p38a) (EC 2.7.11.24) (MAP kinase 14A) (p38 MAPK)
Gene: p38a

Interactor 2: JRA (P18289)
Transcription factor Jra (Jun-related antigen) (Transcription factor AP-1 subunit Jra) (dJRA) (dJun)
Gene: JRA

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	9584193
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0008348 - negative regulation of antimicrobial humoral response
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 366 Dm			1 289
+	Dm
		247434 MK38B_DROME (8-366): 5.79e-149: 426: 79.39		JRA_DROME (1-289): 2.26e-66: 210: 100.00
+	Dm
		576056 ERKA_DROME (2-359): 1.73e-137: 397: 44.11		JRA_DROME (1-289): 2.26e-66: 210: 100.00
+	Hs
		402080 MK14_HUMAN (1-364): 1.59e-145: 417: 67.86		JUN_HUMAN (20-284): 7.34e-42: 148: 29.54
+	Hs
		556876 MK14_HUMAN (1-364): 1.59e-145: 417: 67.86		CREB1_HUMAN (5-267): 6.84e-42: 148: 20.38
+	Sp
		857024 HOG1_SCHPO (8-360): 1.35e-143: 412: 50.85		ATF1_SCHPO (8-278): 2.38e-39: 146: 14.76
+	Hs
		547811 MK14_HUMAN (1-364): 1.59e-145: 417: 67.86		ATF2_HUMAN (3-289): 9.9e-35: 132: 17.12
+	Hs
		401473 MK01_HUMAN (14-354): 5.9e-138: 398: 45.69		JUN_HUMAN (20-284): 7.34e-42: 148: 29.54
+	Hs
		401456 MK03_HUMAN (14-354): 5.5e-137: 396: 46.26		JUN_HUMAN (20-284): 7.34e-42: 148: 29.54
+	Rn
		102456 G3V617_RAT (1-364): 3.45e-146: 419: 67.86		ATF2_RAT (3-289): 1.15e-31: 124: 17.12
+	Hs
		173828 MK13_HUMAN (1-364): 2.73e-142: 409: 55.34		ATF2_HUMAN (3-289): 9.9e-35: 132: 17.12
+	Mm
		562973 MK14_MOUSE (1-364): 5.53e-146: 418: 67.86		ATF2_MOUSE (3-289): 2.61e-31: 123: 17.12
+	Hs
		568066 MK01_HUMAN (14-354): 5.9e-138: 398: 45.69		JUND_HUMAN (21-285): 1.35e-38: 140: 26.90
+	Hs
		547805 MK11_HUMAN (1-352): 4.18e-140: 404: 64.21		ATF2_HUMAN (3-289): 9.9e-35: 132: 17.12
+	Hs
		579344 MK14_HUMAN (1-364): 1.59e-145: 417: 67.86		ATF6A_HUMAN (41-267): 2.83e-28: 115: 14.47
+	Mm
		562985 MK11_MOUSE (1-362): 8.87e-142: 408: 63.54		ATF2_MOUSE (3-289): 2.61e-31: 123: 17.12
+	Hs
		547713 MK01_HUMAN (14-354): 5.9e-138: 398: 45.69		ATF2_HUMAN (3-289): 9.9e-35: 132: 17.12
+	Hs
		547709 MK03_HUMAN (14-354): 5.5e-137: 396: 46.26		ATF2_HUMAN (3-289): 9.9e-35: 132: 17.12
+	Mm
		562975 MK01_MOUSE (14-354): 4.94e-138: 398: 45.69		ATF2_MOUSE (3-289): 2.61e-31: 123: 17.12
+	Mm
		562980 MK03_MOUSE (15-359): 1.36e-137: 398: 45.74		ATF2_MOUSE (3-289): 2.61e-31: 123: 17.12
+	Dm
		599211 ERKA_DROME (2-359): 1.73e-137: 397: 44.11		FOSLA_DROME (133-281): 2.27e-24: 104: 18.79