Interactor 1: GSDME (O60443)
Gasdermin-E (Inversely correlated with estrogen receptor expression 1) (ICERE-1) (Non-syndromic hearing impairment protein 5) [Cleaved into: Gasdermin-E, N-terminal (GSDME-NT); Gasdermin-E, C-terminal (GSDME-CT)]
Gene: GSDME
Interactor 2: GSDMD (P57764)
Gasdermin-D (Gasdermin domain-containing protein 1) [Cleaved into: Gasdermin-D, N-terminal (GSDMD-NT) (hGSDMD-NTD); Gasdermin-D, C-terminal (GSDMD-CT) (hGSDMD-CTD); Gasdermin-D, p13 (Gasdermin-D, 13 kDa) (13 kDa GSDMD); Gasdermin-D, p40]
Gene: GSDMD
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.33 | 1.00 | 0.575 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | unassigned3799 |
| Identification Methods | anti tag coimmunoprecipitation |
| Interaction Type | association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Gasdermin~Gasdermin, Gasdermin~Gasdermin_C, Gasdermin_C~Gasdermin_C |
| Common GO terms | GO:0005546 - phosphatidylinositol-4,5-bisphosphate binding GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane GO:0022829 - wide pore channel activity and 3 others more... |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Mm |   |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 11Aug2025
